Objective: To estimate lung cancer incidence and mortality in China using population-based cancer registry data in 2014 collected by National Central Cancer Registry of China (NCCRC). Methods: 449 cancer registries submitted cancer registry data in 2014. All datasets were evaluated and 339 registries' data which met the quality control criteria of NCCRC were analyzed. Numbers of new lung cancer cases and deaths were estimated using calculated incidence and mortality rates and corresponding national population stratified by areas, sexes and age groups. The standard population of Chinese census in 2000 and world Segi' s population were applied to calculate age-standardized incidence and mortality rates in China and worldwide, respectively. Results: A total of 781, 500 new lung cancer cases were diagnosed in 2014. The crude incidence rate was 57.13 per 100 000 and the age-standardized incidence rates by Chinese standard population (ASIRC) and by world standard population (ASIRW) were 36.71 per 100 000 and 36.63 per 100 000, respectively. The cumulative incidence rate (0-74 years old) was 4.50%. Lung cancer was the most common cancer in male (ASIRW: 50.04 per 100 000) and the second most common cancer in female (ASIRW: 23.63 per 100 000). The incidence rates were slightly similar in urban areas and in rural areas (ASIRW: 36.64 per 100 000 vs 36.56 per 100 000). A total of 626 400 lung cancer deaths were reported. The crude mortality rate was 45.80 per 100 000 and the age-standardized mortality rates by Chinese standard population (ASMRC) and by world standard population (ASMRW) were 28.49 per 100 000 and 28.31 per 100 000, respectively. The cumulative mortality rate (0-74 years old) was 3.32%. Lung cancer was the most common cause of cancer deaths both in male (ASMRW: 40.21 per 100 000) and female (ASMRW: 16.88 per 100 000). The mortality rate was slightly higher in rural areas than in urban areas (ASMRW: 28.63 per 100 000 vs 28.04 per 100 000). Both lung cancer incidence and mortality rates increased with age, and the peak age was 80-84 years group. Conclusions: The disease burden of lung cancer is heavy in China. Efficient national health policies and prevention and control strategies against lung cancer should be promoted.
目的： 分析全国各登记处上报的2014年以人群为基础的恶性肿瘤登记数据，估计中国的肺癌发病和死亡情况。 方法： 全国肿瘤登记中心共收到全国449个登记处上报的2014年肿瘤登记数据，经过严格的质量控制后，339个登记中心的数据符合标准。结合2014年全国人口数据，估计中国肺癌的发病和死亡情况。中国人口标化率(中标率)采用2000年中国人口普查的标准人口年龄构成进行标化，世界人口标化率(世标率)采用Segi′s标准人口年龄构成进行标化。 结果： 2014年中国肺癌估计新发病例78.15万例，发病率为57.13/10万，中标发病率为36.71/10万，世标发病率为36.63/10万，0～74岁累积发病率为4.50%。肺癌发病率在中国男性恶性肿瘤中位居第1位，在中国女性恶性肿瘤中位居第2位，世标发病率分别为50.04/10万和23.63/10万。城市地区和农村地区的肺癌世标发病率相近，分别为36.64/10万和36.56/10万。2014年中国肺癌估计死亡病例62.64万例，死亡率为45.80/10万，中标死亡率为28.49/10万，世标死亡率为28.31/10万，0～74岁累积死亡率为3.32%。肺癌在中国男性、女性人群中均为死亡率最高的恶性肿瘤，世标死亡率分别为40.21/10万和16.88/10万。农村地区肺癌世标死亡率略高于城市地区，分别为28.63/10万和28.04/10万。肺癌发病率和死亡率均随年龄的增长而升高，并在80～84岁组达到峰值。 结论： 中国肺癌疾病负担沉重，应在全国范内积极开展针对肺癌的综合防治措施。.
Keywords: Cancer registry; China; Incidence; Lung neoplasms; Mortality.