Nondepolarizing Neuromuscular Blockers

Excerpt

Nondepolarizing neuromuscular blockers (nNMBs) are primarily administered to facilitate endotracheal intubation and serve as adjuvant therapy during the perioperative maintenance of anesthesia and care for critically ill patients. Agents such as rocuronium, vecuronium, pancuronium, atracurium, cisatracurium, and mivacurium are specifically used to enhance airway management and reduce the risk of laryngeal injury during both routine and emergency intubations. These medications also improve mechanical ventilation outcomes in critically ill patients. nNMBs have several indications approved by the US Food and Drug Administration (FDA), primarily focused on improving airway management, surgical procedures, and mechanical ventilation.