Emerging corneal pathogens: First report of Pseudopestalotiopsis theae keratitis

Indian J Ophthalmol. 2019 Jan;67(1):150-152. doi: 10.4103/ijo.IJO_791_18.

Abstract

A 55-year-old lady developed a corneal ring infiltrate following trauma with a wooden stick. 10% KOH mount of corneal scrapings revealed septate hyaline fungal filaments. White feathery colonies with shiny black dots grew on potato dextrose agar. Characteristic features of Pestalotiopsis spores were seen on Lactophenol cotton blue mount. DNA sequencing showed 99% similarity with Pseudopestalotiopsis theae. Complete resolution was noted with topical and oral antifungals. To the best of our knowledge, this is the first report of Pseudopestalotiopsis keratitis following trauma with vegetative matter highlighting the role of DNA sequencing in identification of rare fungi.

Keywords: Fungal keratitis; Pseudopestalotiopsis theae; phylogenetic analysis; trauma.

Publication types

  • Case Reports

MeSH terms

  • Antifungal Agents / therapeutic use*
  • Cornea / microbiology
  • Cornea / pathology*
  • Corneal Ulcer / diagnosis*
  • Corneal Ulcer / drug therapy
  • Corneal Ulcer / microbiology
  • Eye Infections, Fungal / diagnosis*
  • Eye Infections, Fungal / drug therapy
  • Eye Infections, Fungal / microbiology
  • Female
  • Fungi / isolation & purification*
  • Humans
  • Middle Aged

Substances

  • Antifungal Agents