Awareness of Female Cancer Patients About the Risk of Impaired Fertility

J Adolesc Young Adult Oncol. 2019 Jun;8(3):342-348. doi: 10.1089/jayao.2018.0112. Epub 2018 Dec 24.

Abstract

Purpose: To evaluate awareness of female cancer patients about fertility impairment following cancer treatment. Patients and Methods: This cross-sectional study was conducted in Imam Hossein Hospital between March 2014 and July 2015. Women of childbearing age with cancer who were treated in an oncology clinic and referred for follow-up were asked to fill out the questionnaire designed for this purpose. The process of filling out the questionnaire was managed by a resident of clinical oncology during patient interviews. Results: Two hundred forty-seven patients with mean age of 35.5 years were included. The most common cancers were breast cancer (61.9%) and gynecologic cancer (10.9%). Among all patients, 22.7% had received information about infertility risk. The likelihood that women would have received information about fertility varied by cancer type. Among women with gynecologic cancers, only 59.3% had received information about the effects of treatment on fertility despite having cancers of the reproductive system. Moreover, 19.6% of women with breast cancer and 18.5% of those with other cancers had received fertility information (p < 0.001). Significance of Results: Knowledge and awareness of female cancer patients of childbearing age about the impact of cancer treatment on fertility and fertility preservation are limited. A structured program is required to provide complete information regarding the risk of fertility impairment following cancer treatment and increase the knowledge of these patients to enable them to make a proper decision about fertility preservation.

Keywords: breast cancer; cancer; chemotherapy; infertility; radiotherapy.

MeSH terms

  • Adult
  • Breast Neoplasms / complications*
  • Cross-Sectional Studies
  • Female
  • Fertility / physiology*
  • Fertility Preservation / methods*
  • Humans
  • Infertility, Female / psychology*
  • Middle Aged
  • Young Adult