Neurologic Manifestations of Influenza A(H3N2) Infection in Children During the 2016-2017 Season

J Pediatric Infect Dis Soc. 2020 Feb 28;9(1):71-74. doi: 10.1093/jpids/piy130.

Abstract

Among 182 children with influenza infection in 2016-2017, 18% had neurologic manifestations of influenza (NMI), including seizures and encephalopathy; 85% of these children were infected with the H3N2 strain. Children with NMI had 3.5-times-higher odds of having a neurologic comorbidity than those without NMI and a 10-fold increased odds of hospitalization.

Keywords: encephalitis; encephalopathy; influenza; neurologic manifestation; pediatric; seizures.

MeSH terms

  • Brain Diseases / virology
  • Case-Control Studies
  • Child
  • Child, Preschool
  • Colorado
  • Confusion / virology
  • Encephalitis, Viral / virology
  • Female
  • Hospitalization
  • Humans
  • Influenza A Virus, H3N2 Subtype*
  • Influenza, Human / complications*
  • Influenza, Human / virology
  • Male
  • Nervous System Diseases / virology*
  • Retrospective Studies
  • Risk Factors
  • Seizures / virology*