Dendritic cells mature to resist lamin degradation and herpes virus release

J Cell Biol. 2019 Feb 4;218(2):387-388. doi: 10.1083/jcb.201812051. Epub 2019 Jan 15.

Abstract

Herpes simplex viruses bud into the nuclear membrane of infected cells. Turan et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201801151) demonstrate that mature dendritic cells control the peripheral location of lysosomes, reducing autophagic degradation of lamins and inhibiting viral release.

Publication types

  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Dendritic Cells
  • Herpesvirus 1, Human*
  • Lamins
  • Nuclear Envelope
  • Virus Release

Substances

  • Lamins