Prevalence, Macrolide Resistance, and Fluoroquinolone Resistance in Mycoplasma genitalium in Men Who Have Sex With Men Attending an Sexually Transmitted Disease Clinic in Dublin, Ireland in 2017-2018

Sex Transm Dis. 2019 Apr;46(4):e35-e37. doi: 10.1097/OLQ.0000000000000940.

Abstract

This is the first prevalence study of Mycoplasma genitalium and antimicrobial resistance study in Ireland. In urine samples from men who have sex with men (n = 400) attending a sexually transmitted disease clinic in Dublin, the prevalence of M. genitalium was 3% (12 of 400 specimens; 95% confidence interval, 1.3-4.7%), and the prevalences of macrolide resistance (75%), fluoroquinolone resistance (33.3%), and multidrug resistance (33.3%) were very high.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Anti-Bacterial Agents / pharmacology*
  • Cross-Sectional Studies
  • DNA, Bacterial
  • Drug Resistance, Multiple, Bacterial / genetics*
  • Fluoroquinolones / pharmacology
  • Homosexuality, Male
  • Humans
  • Ireland / epidemiology
  • Macrolides / pharmacology
  • Male
  • Middle Aged
  • Mutation
  • Mycoplasma Infections / epidemiology*
  • Mycoplasma Infections / microbiology
  • Mycoplasma Infections / urine
  • Mycoplasma genitalium / drug effects*
  • Mycoplasma genitalium / genetics
  • Prevalence
  • RNA, Ribosomal, 23S / genetics
  • Young Adult

Substances

  • Anti-Bacterial Agents
  • DNA, Bacterial
  • Fluoroquinolones
  • Macrolides
  • RNA, Ribosomal, 23S