Toward a Core Outcome Measurement Set for Polymyalgia Rheumatica: Report from the OMERACT 2018 Special Interest Group

Claire E Owen; Max Yates; Helen Twohig; Sara Muller; Lorna M Neill; Eileen Harrison; Beverley Shea; Lee S Simon; Catherine L Hill; Sarah L Mackie

doi:10.3899/jrheum.181050

Toward a Core Outcome Measurement Set for Polymyalgia Rheumatica: Report from the OMERACT 2018 Special Interest Group

J Rheumatol. 2019 Oct;46(10):1360-1364. doi: 10.3899/jrheum.181050. Epub 2019 Feb 1.

Authors

Claire E Owen^{1

2}, Max Yates^{3

4}, Helen Twohig^{3

4}, Sara Muller^{3

4}, Lorna M Neill^{3

4}, Eileen Harrison^{3

4}, Beverley Shea^{3

4}, Lee S Simon^{3

4}, Catherine L Hill^{3

4}, Sarah L Mackie^{3

4}

Affiliations

¹ From the Department of Rheumatology, Austin Health; Department of Medicine, University of Melbourne, Melbourne; Rheumatology Unit, Royal Adelaide Hospital; Discipline of Medicine, The University of Adelaide, Adelaide, Australia; Department of Rheumatology, Addenbrooke's Hospital, Cambridge; Norwich Medical School, University of East Anglia, Norwich; Arthritis Research UK Primary Care Centre, Primary Care Sciences, Keele University, Keele; PMR-GCA Scotland, Dundee, Angus; PMR-GCA North East, Kibblesworth, Tyne and Wear; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; UK National Institute for Health Research (NIHR)-Leeds Biomedical Research Centre, Leeds Teaching Hospitals National Health Service (NHS) Trust, Leeds, UK; Ottawa Hospital Research Institute; School of Epidemiology, Public Health and Preventative Medicine, University of Ottawa, Ottawa, Ontario, Canada; SDG LLC, Cambridge, Massachusetts, USA. claire.owen@austin.org.au.
² C.E. Owen, MBBS (Hons), Consultant Rheumatologist, Department of Rheumatology, Austin Health, and Department of Medicine, University of Melbourne; M. Yates, PhD, Clinical Research Fellow, Department of Rheumatology, Addenbrooke's Hospital, and Norwich Medical School, University of East Anglia; H. Twohig, MBChB, General Practitioner, Arthritis Research UK Primary Care Centre, Primary Care Sciences, Keele University; S. Muller, PhD, Senior Research Fellow, Arthritis Research UK Primary Care Centre, Primary Care Sciences, Keele University; L.M. Neill, BSc, OMERACT, Patient Research Partner, PMR-GCA Scotland; E. Harrison, BSc, OMERACT, Patient Research Partner, PMR-GCA North East; B. Shea, PhD, Senior Methodologist and Adjunct Professor, Ottawa Hospital Research Institute, and School of Epidemiology, Public Health and Preventative Medicine, University of Ottawa; L.S. Simon, MD, Principal, SDG LLC; C.L. Hill, MD, Clinical Professor and Consultant Rheumatologist, Rheumatology Unit, Royal Adelaide Hospital, and Discipline of Medicine, The University of Adelaide; S.L. Mackie, PhD, Associate Clinical Professor and Consultant Rheumatologist, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR-Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust. claire.owen@austin.org.au.
³ From the Department of Rheumatology, Austin Health; Department of Medicine, University of Melbourne, Melbourne; Rheumatology Unit, Royal Adelaide Hospital; Discipline of Medicine, The University of Adelaide, Adelaide, Australia; Department of Rheumatology, Addenbrooke's Hospital, Cambridge; Norwich Medical School, University of East Anglia, Norwich; Arthritis Research UK Primary Care Centre, Primary Care Sciences, Keele University, Keele; PMR-GCA Scotland, Dundee, Angus; PMR-GCA North East, Kibblesworth, Tyne and Wear; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; UK National Institute for Health Research (NIHR)-Leeds Biomedical Research Centre, Leeds Teaching Hospitals National Health Service (NHS) Trust, Leeds, UK; Ottawa Hospital Research Institute; School of Epidemiology, Public Health and Preventative Medicine, University of Ottawa, Ottawa, Ontario, Canada; SDG LLC, Cambridge, Massachusetts, USA.
⁴ C.E. Owen, MBBS (Hons), Consultant Rheumatologist, Department of Rheumatology, Austin Health, and Department of Medicine, University of Melbourne; M. Yates, PhD, Clinical Research Fellow, Department of Rheumatology, Addenbrooke's Hospital, and Norwich Medical School, University of East Anglia; H. Twohig, MBChB, General Practitioner, Arthritis Research UK Primary Care Centre, Primary Care Sciences, Keele University; S. Muller, PhD, Senior Research Fellow, Arthritis Research UK Primary Care Centre, Primary Care Sciences, Keele University; L.M. Neill, BSc, OMERACT, Patient Research Partner, PMR-GCA Scotland; E. Harrison, BSc, OMERACT, Patient Research Partner, PMR-GCA North East; B. Shea, PhD, Senior Methodologist and Adjunct Professor, Ottawa Hospital Research Institute, and School of Epidemiology, Public Health and Preventative Medicine, University of Ottawa; L.S. Simon, MD, Principal, SDG LLC; C.L. Hill, MD, Clinical Professor and Consultant Rheumatologist, Rheumatology Unit, Royal Adelaide Hospital, and Discipline of Medicine, The University of Adelaide; S.L. Mackie, PhD, Associate Clinical Professor and Consultant Rheumatologist, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR-Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust.

PMID: 30709960
DOI: 10.3899/jrheum.181050

Abstract

Objective: To report the progress of the Outcome Measures in Rheumatology (OMERACT) Polymyalgia Rheumatica (PMR) Working Group in selecting candidate instruments for a core outcome measurement set.

Methods: A systematic literature review identified outcomes measured and instruments used in PMR studies, and a respondent survey and raw data analysis assessed their domain match and feasibility.

Results: Candidate instruments were identified for pain [visual analog scale/numerical rating scale (VAS/NRS)], stiffness (VAS/NRS and duration), and physical function (Health Assessment Questionnaire-Disability Index/modified Health Assessment Questionnaire). Domain match and feasibility assessments were favorable; however, validation in PMR was lacking.

Conclusion: Further assessment of candidate instruments is required prior to recommending a PMR core outcome measurement set.

Keywords: OMERACT; OUTCOMES; POLYMYALGIA RHEUMATICA.

Publication types

Systematic Review

MeSH terms

Adult
Aged
Aged, 80 and over
Blood Sedimentation
C-Reactive Protein / analysis
Feasibility Studies
Female
Health Surveys
Humans
Male
Middle Aged
Outcome Assessment, Health Care / methods*
Pain
Pain Measurement
Polymyalgia Rheumatica / physiopathology*
Polymyalgia Rheumatica / therapy*
Public Opinion
Visual Analog Scale

Substances

C-Reactive Protein

Abstract

Publication types

MeSH terms

Substances

Grants and funding