Skin inflammation associated with arthritis, synovitis and enthesitis. Part 2: rheumatoid arthritis, reactive arthritis, Reiter's syndrome, Lyme borreliosis, dermatomyositis and lupus erythematosus

J Dtsch Dermatol Ges. 2019 Feb;17(2):167-181. doi: 10.1111/ddg.13761.

Abstract

Syndromes associated with concurrent skin and joint inflammation frequently pose a therapeutic challenge for both dermatologists and rheumatologists. In part 1 of this review, we discussed psoriatic arthritis as well as the autoinflammatory disorders SAPHO syndrome, Still's disease and Behçet's disease. Part 2 will address rheumatoid arthritis, reactive arthritis, Reiter's syndrome and Lyme borreliosis. In addition, we will discuss dermatomyositis and lupus erythematosus, two common autoimmune disorders that frequently present with both cutaneous and joint involvement. For each of the aforementioned disorders, we will highlight aspects of epidemiology, pathogenesis, clinical presentation, diagnosis and treatment.

Publication types

  • Review

MeSH terms

  • Arthritis, Reactive / epidemiology
  • Arthritis, Reactive / pathology
  • Arthritis, Reactive / therapy
  • Arthritis, Rheumatoid / complications
  • Arthritis, Rheumatoid / epidemiology
  • Arthritis, Rheumatoid / pathology
  • Arthritis, Rheumatoid / therapy
  • Autoimmune Diseases / epidemiology
  • Autoimmune Diseases / pathology
  • Dermatomyositis / complications
  • Dermatomyositis / epidemiology
  • Dermatomyositis / pathology
  • Dermatomyositis / therapy
  • Enthesopathy / complications*
  • Enthesopathy / epidemiology
  • Enthesopathy / pathology
  • Hereditary Autoinflammatory Diseases / epidemiology
  • Hereditary Autoinflammatory Diseases / pathology
  • Humans
  • Inflammation / etiology*
  • Lupus Erythematosus, Systemic / complications
  • Lupus Erythematosus, Systemic / epidemiology
  • Lupus Erythematosus, Systemic / pathology
  • Lupus Erythematosus, Systemic / therapy
  • Lyme Disease / complications
  • Lyme Disease / epidemiology
  • Lyme Disease / pathology
  • Lyme Disease / therapy
  • Prevalence
  • Skin / pathology*
  • Synovitis / complications*
  • Synovitis / epidemiology
  • Synovitis / pathology
  • Synovitis / therapy