Nutritional management in renal transplant recipients: A transplant team opportunity to improve graft survival

Nutr Metab Cardiovasc Dis. 2019 Apr;29(4):319-324. doi: 10.1016/j.numecd.2019.01.002. Epub 2019 Jan 12.

Abstract

Aims: The nutritional management of renal transplant recipients (RTR) represents a complex problem either because the recovery of renal function is not complete and for the appearance of "unavoidable" metabolic side effects of immunosuppressive drugs. Nevertheless, it remains a neglected problem, whereas an appropriate dietary intervention could favorably affect graft survival.

Data synthesis: Renal transplantation is associated with steroids and calcineurin inhibitors administration, liberalization of diet after dialysis restrictions, and patients' better quality of life. These factors predispose, from the first months after surgery, to body weight gain, enhanced post transplant diabetes, hyperlipidemia, metabolic syndrome, with negative consequences on graft outcome. Unfortunately, specific guidelines about this topic and nutritional counseling are scarce; moreover, beyond the low adherence of patients to any dietary plan, there is a dangerous underestimation of the problem by physicians, sometimes with inadequate interventions. A prompt and specific nutritional management of RTR can help prevent or minimize these metabolic alterations, mostly when associated with careful and repeated counseling.

Conclusions: A correct nutritional management, possibly tailored to enhance patients' motivation and adherence, represents the best preventive maneuver to increase patients' life and probably improve graft survival, at no cost and with no side effects.

Keywords: Chronic kidney disease; Dietary adherence; Nutritional management; Renal transplantation.

MeSH terms

  • Diet, Healthy
  • Graft Survival*
  • Humans
  • Immunosuppressive Agents / adverse effects
  • Kidney Transplantation* / adverse effects
  • Nutrition Disorders / etiology
  • Nutrition Disorders / physiopathology
  • Nutrition Disorders / prevention & control*
  • Nutrition Therapy / methods*
  • Nutritional Status*
  • Quality of Life
  • Risk Factors
  • Time Factors
  • Treatment Outcome

Substances

  • Immunosuppressive Agents