Infusion efficiency of sodium fluorescein into various starches

Food Sci Biotechnol. 2018 Aug 22;28(1):99-102. doi: 10.1007/s10068-018-0455-5. eCollection 2019 Feb.

Abstract

The objective of this study was to develop new drug delivery systems (DDS) and nutrient delivery systems (NDS), using starch as a carrier material for infusion technology. Corn, waxy rice, non-waxy rice, and potato starches were used as carrier materials. Sodium fluorescein was used as an infusion material for easy detection. Each starch suspension with sodium fluorescein was reacted in a water bath at 40, 50, and 60 °C for 30 min. After each reaction, the concentration of sodium fluorescein in the supernatant was measured using a fluorescence detector. Precipitated starch was observed using fluorescence microscopy. About 70% of sodium fluorescein infused in waxy rice and corn starches at 60 °C. Additionally, the granules of these two starches were luminous by green light when exposed to a fluorescence detector, suggesting that corn and waxy rice starches can be used as carrier materials in infusion technology for DDS and NDS.

Keywords: Drug delivery system; Infusion; Nutrient delivery system; Sodium fluorescein; Starch.