Abstract
Three women with systemic lupus erythematosus (SLE) who developed pulmonary hypertension as a terminal feature of their illness, are reported. One patient with quiescent SLE had marked sicca syndrome when pulmonary hypertension developed. Two of the 3 patients possessed the "lupus anticoagulant" and antibodies to cardiolipin. All 3 patients had positive rheumatoid factor in their sera.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Autoantibodies / analysis
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Blood Coagulation Factors / analysis
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Blood Coagulation Factors / antagonists & inhibitors
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Cardiolipins / immunology
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Female
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Humans
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Hypertension, Pulmonary / drug therapy
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Hypertension, Pulmonary / etiology*
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Lupus Coagulation Inhibitor
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Lupus Erythematosus, Systemic / complications*
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Lupus Erythematosus, Systemic / immunology
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Middle Aged
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Vasodilator Agents / therapeutic use
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Xerophthalmia / etiology
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Xerostomia / etiology
Substances
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Autoantibodies
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Blood Coagulation Factors
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Cardiolipins
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Lupus Coagulation Inhibitor
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Vasodilator Agents