A Critical Evaluation of Current Concepts in Cerebral Palsy

Physiology (Bethesda). 2019 May 1;34(3):216-229. doi: 10.1152/physiol.00054.2018.

Abstract

Spastic cerebral palsy (CP), despite the name, is not consistently identifiable by specific brain lesions. CP animal models focus on risk factors for development of CP, yet few reproduce the diagnostic symptoms. Animal models of CP must advance beyond risk factors to etiologies, including both the brain and spinal cord.

Publication types

  • Review

MeSH terms

  • Animals
  • Brain / pathology
  • Cerebral Palsy* / etiology
  • Cerebral Palsy* / pathology
  • Cerebral Palsy* / physiopathology
  • Disease Models, Animal*
  • Humans
  • Risk Factors