French translation and linguistic validation of the Raynaud's condition score

Charles Khouri; Sophie Blaise; Alicia Guigui; Claire Cracowski; Yannick Allanore; Eric Hachulla; Patricia Senet; Mathieu Roustit; Jean-Luc Cracowski

doi:10.1016/j.therap.2019.03.002

French translation and linguistic validation of the Raynaud's condition score

Therapie. 2019 Dec;74(6):627-631. doi: 10.1016/j.therap.2019.03.002. Epub 2019 Apr 2.

Authors

Charles Khouri¹, Sophie Blaise², Alicia Guigui³, Claire Cracowski³, Yannick Allanore⁴, Eric Hachulla⁵, Patricia Senet⁶, Mathieu Roustit⁷, Jean-Luc Cracowski⁷

Affiliations

¹ Pharmacovigilance unit, Grenoble Alpes university hospital, 38000 Grenoble, France; Inserm CIC1406, clinical pharmacology department, Grenoble Alpes university hospital, 38000 Grenoble, France; Inserm, UMR 1042-HP2, university Grenoble Alpes, 38000 Grenoble, France. Electronic address: CKhouri@chu-grenoble.fr.
² Inserm, UMR 1042-HP2, university Grenoble Alpes, 38000 Grenoble, France; Department of vascular medicine, Grenoble university hospital, 38000 Grenoble, France.
³ Inserm CIC1406, clinical pharmacology department, Grenoble Alpes university hospital, 38000 Grenoble, France.
⁴ Service de rhumatologie A, hôpital Cochin, université Paris Descartes, 75014 Paris, France.
⁵ Service de médecine interne, Centre de référence des maladies auto-immunes systémiques rares du Nord et Nord-Ouest de France (CeRAINO), hôpital Claude Huriez, CHU de Lille, 59045 Lille, France.
⁶ Service de dermatologie et allergologie, hôpital Tenon, groupe hospitalier universitaire Paris Est, Assistance publique-Hôpitaux de Paris, 75020 Paris, France.
⁷ Inserm CIC1406, clinical pharmacology department, Grenoble Alpes university hospital, 38000 Grenoble, France; Inserm, UMR 1042-HP2, university Grenoble Alpes, 38000 Grenoble, France.

PMID: 31023622
DOI: 10.1016/j.therap.2019.03.002

Abstract

The Raynaud's condition score is a 11-point scale severity score used in Raynaud's phenomenon clinical trials since 1998. The Raynaud's condition score diary has been recommended for use in clinical trials assessing efficacy of interventions on scleroderma related Raynaud's phenomenon. However, this score has never been formally validated in French. We thus performed a translation and a linguistic validation of the Raynaud's condition score through a forward/backward translations process followed by an expert review and cognitive patient interviews. The translations led to a French version of the Raynaud's condition score that was linguistically valid, and conceptually equivalent to the original English version. This "Score de Raynaud" will be usable to perform and harmonize clinical trials in French-speaking patients with secondary Raynaud's phenomenon.

Keywords: Raynaud's phenomenon; Systemic scleroderma.

Publication types

Validation Study

MeSH terms

Diagnostic Techniques, Cardiovascular* / standards
France
Humans
Interviews as Topic
Language*
Linguistics
Patient Outcome Assessment*
Raynaud Disease / diagnosis*
Raynaud Disease / pathology
Research Design
Scleroderma, Systemic / diagnosis
Scleroderma, Systemic / therapy*
Severity of Illness Index
Translating*
Treatment Outcome