Associations Between Serum Sodium Concentration and Bone Health Measures in Individuals Who Use Antiepileptic Drugs: A Pilot Study

Yeung-Ae Park; Asvini K Subasinghe; Baemisla Shiek Ahmad; Alexandra Gorelik; Suzanne M Garland; Vanessa Clifford; Cherie Chiang; Heather Robinson; John D Wark

doi:10.1016/j.jocd.2019.03.007

Associations Between Serum Sodium Concentration and Bone Health Measures in Individuals Who Use Antiepileptic Drugs: A Pilot Study

J Clin Densitom. 2020 Jul-Sep;23(3):364-372. doi: 10.1016/j.jocd.2019.03.007. Epub 2019 Mar 23.

Authors

Yeung-Ae Park¹, Asvini K Subasinghe², Baemisla Shiek Ahmad³, Alexandra Gorelik⁴, Suzanne M Garland⁵, Vanessa Clifford⁶, Cherie Chiang⁷, Heather Robinson⁸, John D Wark⁹

Affiliations

¹ University of Melbourne, Department of Medicine, Royal Melbourne Hospital, Parkville, Australia. Electronic address: yeungae.park@gmail.com.
² Royal Women's Hospital, Department of Microbiology and Infectious Diseases, Parkville, Australia; Murdoch Children's Research Institute, Infection and Immunity Theme, Parkville, Australia.
³ University of Melbourne, Department of Medicine, Royal Melbourne Hospital, Parkville, Australia.
⁴ University of Melbourne, Department of Medicine, Royal Melbourne Hospital, Parkville, Australia; School of Psychology, Australian Catholic University, Fitzroy, Australia.
⁵ Royal Women's Hospital, Department of Microbiology and Infectious Diseases, Parkville, Australia; Murdoch Children's Research Institute, Infection and Immunity Theme, Parkville, Australia; University of Melbourne, Department of Obstetrics and Gynaecology, Royal Women's Hospital, Parkville, Australia.
⁶ Royal Women's Hospital, Department of Microbiology and Infectious Diseases, Parkville, Australia; Murdoch Children's Research Institute, Infection and Immunity Theme, Parkville, Australia; Department of Pathology, Royal Melbourne Hospital, Parkville, Australia.
⁷ Department of Pathology, Royal Melbourne Hospital, Parkville, Australia.
⁸ Bone and Mineral Medicine, Royal Melbourne Hospital, Parkville, Australia.
⁹ University of Melbourne, Department of Medicine, Royal Melbourne Hospital, Parkville, Australia; Bone and Mineral Medicine, Royal Melbourne Hospital, Parkville, Australia.

PMID: 31036448
DOI: 10.1016/j.jocd.2019.03.007

No abstract available

Keywords: Antiepileptic drugs; bone mineral density; epilepsy; fracture; hyponatraemia.

MeSH terms

Accidental Falls
Adult
Anticonvulsants / therapeutic use*
Carbamazepine / therapeutic use
Epilepsy / drug therapy*
Female
Humans
Hyponatremia / epidemiology*
Levetiracetam / therapeutic use
Male
Middle Aged
Osteoporosis / diagnostic imaging
Osteoporosis / epidemiology*
Osteoporotic Fractures / epidemiology*
Pilot Projects
Risk Factors
Sodium / blood
Valproic Acid / therapeutic use

Substances

Anticonvulsants
Carbamazepine
Levetiracetam
Valproic Acid
Sodium