Mucinous Ovarian Tumors

Surg Pathol Clin. 2019 Jun;12(2):565-585. doi: 10.1016/j.path.2019.01.008.

Abstract

Ovarian mucinous tumors range from benign cystadenomas to borderline tumors to frankly malignant adenocarcinomas, and may display either intestinal-type morphology or, less frequently, endocervical-type differentiation. The latter category has been the subject of recent controversy owing to its morphologic overlap with so-called "seromucinous" ovarian tumors, a group that shares more molecular features with endometrioid tumors than it does with either serous or mucinous ovarian neoplasias. Endocervical-type differentiation in ovarian mucinous tumors may also represent an endocervical metastasis. Distinction of primary ovarian mucinous tumors from gastrointestinal metastases can be difficult, as the morphology of intestinal-type ovarian mucinous primaries sometimes differs only subtly if at all from gastrointestinal metastases.

Keywords: Mucinous adenocarcinoma; Mucinous borderline tumor; Mucinous cystadenoma; Ovarian mucinous tumors.

Publication types

  • Review

MeSH terms

  • Adenocarcinoma, Mucinous / diagnosis
  • Adenocarcinoma, Mucinous / pathology*
  • Biomarkers, Tumor / metabolism
  • Cystadenoma, Mucinous / diagnosis
  • Cystadenoma, Mucinous / pathology*
  • Diagnosis, Differential
  • Female
  • Humans
  • Ovarian Neoplasms / diagnosis
  • Ovarian Neoplasms / pathology*
  • Ovarian Neoplasms / secondary

Substances

  • Biomarkers, Tumor