How physically active do Australian and New Zealander childhood cancer survivors perceive themselves? A report from the ANZCHOG survivorship study

David Mizrahi; Joanna E Fardell; Claire E Wakefield; David Simar; Ann M Maguire; Gill Hubbard; Richard J Cohn; ANZCHOG survivorship study group

doi:10.1016/j.ctim.2019.04.020

How physically active do Australian and New Zealander childhood cancer survivors perceive themselves? A report from the ANZCHOG survivorship study

Complement Ther Med. 2019 Jun:44:196-203. doi: 10.1016/j.ctim.2019.04.020. Epub 2019 Apr 25.

Authors

David Mizrahi¹, Joanna E Fardell², Claire E Wakefield², David Simar³, Ann M Maguire⁴, Gill Hubbard⁵, Richard J Cohn²; ANZCHOG survivorship study group

Affiliations

¹ School of Medical Sciences, UNSW Medicine, UNSW Sydney, Australia; Behavioural Sciences Unit, Kids Cancer Centre, Sydney Children's Hospital, Sydney, Australia. Electronic address: D.Mizrahi@unsw.edu.au.
² Behavioural Sciences Unit, Kids Cancer Centre, Sydney Children's Hospital, Sydney, Australia; School of Women's and Children's Health, UNSW Medicine, UNSW Sydney, Australia.
³ School of Medical Sciences, UNSW Medicine, UNSW Sydney, Australia.
⁴ Institute of Endocrinology and Diabetes, The Children's Hospital at Westmead, Sydney, Australia; Discipline of Child and Adolescent Health, Sydney Medical School, The University of Sydney, Sydney, Australia.
⁵ Department of Nursing, Centre for Health Sciences, University of the Highlands and Islands, Inverness, United Kingdom.

PMID: 31126556
DOI: 10.1016/j.ctim.2019.04.020

Abstract

Purpose: Childhood cancer survivors are at risk of treatment late-effects. Physical activity represents a necessary complementary therapy and modifiable risk-factor across all ages for many cardio-metabolic late-effects. This study assessed perceived physical activity in Australian and New Zealander childhood cancer survivors.

Methods: We recruited parents of survivors aged <16 years, and adult survivors of childhood cancer aged ≥16 years, ≥5 years since diagnosis, with age-matched controls for comparison. We compared perceived moderate-vigorous physical activity between survivors and controls, using regression to identify associations with physical activity.

Results: We recruited 914 participants (570 childhood cancer survivors and 344 age-matched controls). Parents of survivors perceived more moderate-vigorous physical activity than child controls (248 ± 218, 95% Confidence Interval (CI) = 218-280 vs 185 ± 214 min/week, 95% CI = 144-225, p = 0.036), with no perceived difference between adult survivors and controls (125 ± 152, 95% CI = 108-140 vs 160 ± 201 min/week, 95% CI = 132-187, p = 0.477). Twenty-seven percent of child survivors (vs. 14.5% controls) and 30% of adult survivors (vs. 39.4% controls) met recommendations. Adult survivors who received radiotherapy (OR = 0.585, 95% CI = 0.343-0.995, p = 0.048) or not completed university (OR = 1.808, 95% CI = 1.071-3.053, p = 0.027) were less likely to meet recommendations.

Conclusions: Over two-thirds of Australian and New Zealander childhood cancer survivors across all ages are perceived to not meet physical activity recommendations. Adult survivors who had radiotherapy or did not complete university appeared at-risk for low physical activity.

Practical implications: Physical activity is important for everyone, but critical among childhood cancer survivors due to increased late cardio-metabolic risks. Monitoring survivors' perceived but also objectively measured physical activity as complementary to routine care is warranted, to provide education and motivate survivors to take control of their health.

Keywords: Chemotherapy; Complementary medicine; Exercise; Physical activity; Radiotherapy; Survivorship.

MeSH terms

Adolescent
Adult
Australia
Cancer Survivors
Case-Control Studies
Child
Exercise / physiology*
Female
Humans
Male
Neoplasms / physiopathology*
New Zealand
Parents
Perception / physiology*
Racial Groups
Risk Factors
Survivorship
Young Adult