[Drug treatment of Alzheimer's dementia : Status quo and perspectives]

Internist (Berl). 2019 Jul;60(7):761-768. doi: 10.1007/s00108-019-0625-4.
[Article in German]

Abstract

Alzheimer's disease (AD) is a neurodegenerative disease of the central nervous system. AD is characterized by progressive impairments of memory as well as other cognitive functions and an increasing loss of autonomy in everyday life. This review article provides an overview of the current state-of-the-art (symptomatic) pharmacological treatment of Alzheimer's disease, specifics in the context of concomitant neuropsychiatric symptoms in multimorbid patients, and drugs currently under development that have a potentially causal (disease modifying) effect are also mentioned.

Keywords: Aging; Alzheimer disease, prevention; Cholinesterase inhibitors; Memantine; Multimorbidity.

Publication types

  • Review

MeSH terms

  • Alzheimer Disease / drug therapy*
  • Cholinesterase Inhibitors / therapeutic use*
  • Humans
  • Memantine / therapeutic use*
  • Neurodegenerative Diseases / complications

Substances

  • Cholinesterase Inhibitors
  • Memantine