A Rare Fusion of CLIP1 and ALK in a Case of Non-Small-Cell Lung Cancer With Neuroendocrine Features

Clin Lung Cancer. 2019 Sep;20(5):e535-e540. doi: 10.1016/j.cllc.2019.05.001. Epub 2019 May 11.
No abstract available

Keywords: ALK rearrangement; CLIP1; Fusion variants; Neuroendocrine carcinoma; RNA sequencing.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Anaplastic Lymphoma Kinase / genetics*
  • Biomarkers, Tumor
  • Carcinoma, Neuroendocrine / diagnosis
  • Carcinoma, Neuroendocrine / genetics*
  • Carcinoma, Non-Small-Cell Lung / diagnosis
  • Carcinoma, Non-Small-Cell Lung / genetics*
  • Female
  • Gene Rearrangement
  • High-Throughput Nucleotide Sequencing
  • Humans
  • Lung Neoplasms / diagnosis
  • Lung Neoplasms / genetics*
  • Microtubule-Associated Proteins / genetics*
  • Neoplasm Proteins / genetics*
  • Neoplasm Staging
  • Neurosecretory Systems / physiology*
  • Oncogene Proteins, Fusion / genetics*
  • Sequence Analysis, RNA

Substances

  • Biomarkers, Tumor
  • Microtubule-Associated Proteins
  • Neoplasm Proteins
  • Oncogene Proteins, Fusion
  • cytoplasmic linker protein 170
  • ALK protein, human
  • Anaplastic Lymphoma Kinase