Optical coherence tomography angiography in Purtscher-like retinopathy associated with dermatomyositis: a case report

J Med Case Rep. 2019 Jul 6;13(1):206. doi: 10.1186/s13256-019-2152-2.

Abstract

Purpose: To describe a multimodal imaging diagnosis of retinopathy in dermatomyositis.

Case presentation: A 21-year-old white woman with a history of fatigue and a cutaneous rash complained of visual impairment in her left eye. A funduscopic examination showed multiple confluent cotton-wool spots in both eyes. Swept source-optical coherence tomography presented macular edema in both eyes; optical coherence tomography angiography revealed superficial and deep capillary occlusion in all areas affected by cotton-wool spots; and fluorescein angiography showed vascular walls enhancement, veins dilatation, and capillary leakage. After large doses of intravenously administered glucocorticoid therapy, followed by a cyclophosphamide regimen, best corrected visual acuity returned to 20/20 in both eyes.

Conclusions: This case report presents optical coherence tomography angiography clinical findings in a rare case of dermatomyositis-associated retinopathy, remarking the importance of a multi-imaging approach for a correct diagnosis and treatment of eye injuries, in order to avoid serious complications and permanent sequelae.

Keywords: Dermatomyositis; OCTA; Retinopathy.

Publication types

  • Case Reports

MeSH terms

  • Administration, Intravenous
  • Cyclophosphamide / administration & dosage
  • Dermatomyositis / complications*
  • Female
  • Fluorescein Angiography
  • Humans
  • Immunosuppressive Agents / administration & dosage
  • Macular Edema / complications*
  • Macular Edema / diagnostic imaging*
  • Macular Edema / drug therapy
  • Macular Edema / pathology
  • Tomography, Optical Coherence / methods*
  • Young Adult

Substances

  • Immunosuppressive Agents
  • Cyclophosphamide