A Triad of Immune Cells Promotes Infection

Marco A Ataide; Wolfgang Kastenmuller

doi:10.1016/j.immuni.2019.06.012

A Triad of Immune Cells Promotes Infection

Immunity. 2019 Jul 16;51(1):5-7. doi: 10.1016/j.immuni.2019.06.012.

Authors

Marco A Ataide¹, Wolfgang Kastenmuller²

Affiliations

¹ Institute for Systems Immunology, Julius Maximilian University of Würzburg, Würzburg, Germany.
² Institute for Systems Immunology, Julius Maximilian University of Würzburg, Würzburg, Germany. Electronic address: wolfgang.kastenmueller@uni-wuerzburg.de.

PMID: 31315036
DOI: 10.1016/j.immuni.2019.06.012

Abstract

The intracellular pathogen L. monocytogenes takes advantage of several myeloid cell populations to establish infection in the spleen. In this issue, Liu et al. (2019) reveal how marginal zone B cells, dendritic cells, and marginal metallophilic macrophages act together with IL-10 to promote L. monocytogenes infection, while simultaneously enabling adaptive CD8⁺ T cell responses.

Publication types

Comment

MeSH terms

Animals
B-Lymphocytes
Dendritic Cells
Interleukin-10
Listeria monocytogenes*
Listeriosis*
Macrophages
Mice

Substances

Interleukin-10