The Consensus Hepatitis C Cascade of Care: Standardized Reporting to Monitor Progress Toward Elimination

Kelly Safreed-Harmon; Sarah Blach; Soo Aleman; Signe Bollerup; Graham Cooke; Olav Dalgard; John F Dillon; Gregory J Dore; Ann-Sofi Duberg; Jason Grebely; Knut Boe Kielland; Håvard Midgard; Kholoud Porter; Homie Razavi; Mark Tyndall; Nina Weis; Jeffrey V Lazarus

doi:10.1093/cid/ciz714

The Consensus Hepatitis C Cascade of Care: Standardized Reporting to Monitor Progress Toward Elimination

Clin Infect Dis. 2019 Nov 27;69(12):2218-2227. doi: 10.1093/cid/ciz714.

Authors

Kelly Safreed-Harmon¹, Sarah Blach², Soo Aleman^{3

4}, Signe Bollerup⁵, Graham Cooke⁶, Olav Dalgard^{7

8}, John F Dillon⁹, Gregory J Dore¹⁰, Ann-Sofi Duberg¹¹, Jason Grebely¹⁰, Knut Boe Kielland¹², Håvard Midgard¹³, Kholoud Porter¹⁴, Homie Razavi², Mark Tyndall¹⁵, Nina Weis^{5

16}, Jeffrey V Lazarus^{1

17}

Affiliations

¹ Barcelona Institute for Global Health (ISGlobal), Hospital Clínic, University of Barcelona, Barcelona, Spain.
² Center for Disease Analysis Foundation, Lafayette, Colorado, USA.
³ Department of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden.
⁴ Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.
⁵ Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Copenhagen, Denmark.
⁶ Department of Infectious Diseases, Imperial College London, London, United Kingdom.
⁷ Department of Infectious Diseases, Akershus University Hospital, Lørenskog, Norway.
⁸ Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
⁹ Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, United Kingdom.
¹⁰ The Kirby Institute, UNSW Sydney, Sydney, Australia.
¹¹ Department of Infectious Diseases, School of Medical Sciences, Örebro University, Örebro, Sweden.
¹² Norwegian National Advisory Unit on Concurrent Substance Abuse and Mental Health Disorders, Innlandet Hospital Trust, Brumunddal, Norway.
¹³ Department of Gastroenterology, Oslo University Hospital, Oslo, Norway.
¹⁴ Institute for Global Health, University College London, London, United Kingdom.
¹⁵ School of Population and Public Health, University of British Columbia, Vancouver, British Columbia, Canada.
¹⁶ Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
¹⁷ CHIP, World Health Organization Collaborating Centre on HIV and Viral Hepatitis, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

PMID: 31352481
DOI: 10.1093/cid/ciz714

Abstract

Cascade-of-care (CoC) monitoring is an important component of the response to the global hepatitis C virus (HCV) epidemic. CoC metrics can be used to communicate, in simple terms, the extent to which national and subnational governments are advancing on key targets, and CoC findings can inform strategic decision-making regarding how to maximize the progression of individuals with HCV to diagnosis, treatment, and cure. The value of reporting would be enhanced if a standardized approach were used for generating CoCs. We have described the Consensus HCV CoC that we developed to address this need and have presented findings from Denmark, Norway, and Sweden, where it was piloted. We encourage the uptake of the Consensus HCV CoC as a global instrument for facilitating clear and consistent reporting via the World Health Organization (WHO) viral hepatitis monitoring platform and for ensuring accurate monitoring of progress toward WHO's 2030 hepatitis C elimination targets.

Keywords: cascade of care; disease elimination; hepatitis C virus; monitoring; policy.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Consensus
Critical Pathways*
Delivery of Health Care*
Disease Management
Global Health
Hepacivirus*
Hepatitis C / diagnosis
Hepatitis C / drug therapy
Hepatitis C / epidemiology*
Humans
Mandatory Reporting
Public Health Surveillance

Abstract

Publication types

MeSH terms

Grants and funding