Discrepancies in access and institutional risk tolerance in heart transplantation: A national open cohort study

J Card Surg. 2019 Oct;34(10):994-1003. doi: 10.1111/jocs.14179. Epub 2019 Aug 2.

Abstract

Background: The impact of center volume on heart transplantation is widely recognized and serves as a benchmark for certification and reimbursement.

Study aims: Study sociodemographic variables associated with access to high-volume centers and substantiate the importance of extending access to underserved populations.

Methods: This study focused on adults undergoing heart transplantation between 2006 and 2015. Centers were clustered into terciles (>25, 14-25, or <14 transplants per year) and factors associated with receiving care in different terciles were identified through multinomial regression.

Results: During the study period, 18 725 patients were transplanted at 145 centers. Younger age (<30 years) (P = .005), lower educational level (P < .001), and government-based insurance (P < .001) were associated to lower odds of receiving care at a high-volume center. These centers had higher risk recipients and accepted organs from higher risk donors, when compared to intermediate- and low-volume centers. Receiving care at high (odds ratio [OR], 1.212; P = .017) and intermediate-volume centers (OR, 1.304; P = .001) was associated with greater odds of 1-year survival when compared with low-volume centers.

Conclusion: Social, demographic, and geographic factors affect access to high- and intermediate-volume centers. High-volume centers tolerate more risk while providing excellent survival. Awareness of this impact should prompt an extension of access to care for underserved patient populations.

Keywords: cardiovascular research; transplant.

Publication types

  • Multicenter Study

MeSH terms

  • Female
  • Follow-Up Studies
  • Graft Survival
  • Heart Transplantation / mortality*
  • Humans
  • Male
  • Middle Aged
  • Odds Ratio
  • Population Surveillance*
  • Registries*
  • Retrospective Studies
  • Risk Assessment / methods*
  • Risk Factors
  • Tissue Donors*
  • Transplantation, Homologous
  • Treatment Outcome
  • United States / epidemiology