Idiopathic basal crux ventricular arrhythmias with left bundle branch block and superior axis: A comparison with inferior-septal valvular arrhythmias

J Cardiovasc Electrophysiol. 2019 Oct;30(10):1914-1922. doi: 10.1111/jce.14103. Epub 2019 Aug 22.

Abstract

Introduction: Left bundle branch block (LBBB) with superior axis is common in patients with idiopathic-ventricular arrhythmia (VA) originating from the tricuspid annulus (TA) and rarely from the cardiac basal crux and mitral annulus (MA). We described the electrocardiography and electrophysiological findings of idiopathic-VA presenting with LBBB and superior axis.

Methods and results: We described 42 idiopathic-VA patients who had an LBBB and superior axis; 15 basal crux-VA, 17 TA-VA, and 10 MA-VA. No patient had a structural heart disease. Among patients with idiopathic-VA referred for ablation, we investigated the electrocardiogram and clinical characteristics of basal crux-VA as compared with other LBBB and superior axis-VA. The left ventricular ejection fraction with MA-VA was significantly lower in comparison with basal crux-VA (P = .01). All patients had a positive R wave in lead I and aVL. The maximum deflection index with basal crux-VA was significantly higher in comparison with TA-VA or MA-VA (P = .01). Patients with basal crux-VA presented with QS wave in lead II more frequently as compared with TA-VA or MA-VA (P = .001). All MA-VA patients had Rs wave in V6, and basal crux-VA, and TA-VA patients had a monophasic R wave or Rs wave in V6. Basal crux-VA patients underwent ablation in the middle cardiac vein (MCV) or coronary sinus (success rate: 94%, recurrence rate: 6%).

Conclusions: We could distinguish basal crux-VA, TA-VA, and MA-VA, using a combination of clinical and electrocardiographic findings. These findings might be useful for counseling patients about an ablation strategy. Ablation via the MCV is effective for eliminating basal crux-VA.

Keywords: LBBB; cardiac crux; catheter ablation; valvular arrhythmia; ventricular tachycardia.

Publication types

  • Comparative Study

MeSH terms

  • Action Potentials*
  • Adult
  • Aged
  • Bundle-Branch Block / diagnosis*
  • Bundle-Branch Block / physiopathology
  • Catheter Ablation
  • Coronary Sinus / physiopathology*
  • Coronary Sinus / surgery
  • Electrocardiography*
  • Electrophysiologic Techniques, Cardiac*
  • Female
  • Heart Rate*
  • Humans
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Recurrence
  • Stroke Volume
  • Tachycardia, Ventricular / diagnosis*
  • Tachycardia, Ventricular / physiopathology
  • Tachycardia, Ventricular / surgery
  • Treatment Outcome
  • Ventricular Function, Left