Paediatric acute lymphoblastic leukaemia causing acute leukaemic occlusion of the proximal middle cerebral artery: Treatment with endovascular thrombectomy

Joshua Mahadevan; Stephen Bacchi; Michelle Kiley; Lynette Moore; Rebecca Manudhane; Manika Pal; Rebecca Scroop; Timothy Kleinig

doi:10.1016/j.jocn.2019.07.075

Paediatric acute lymphoblastic leukaemia causing acute leukaemic occlusion of the proximal middle cerebral artery: Treatment with endovascular thrombectomy

J Clin Neurosci. 2019 Oct:68:336-338. doi: 10.1016/j.jocn.2019.07.075. Epub 2019 Aug 8.

Authors

Joshua Mahadevan¹, Stephen Bacchi², Michelle Kiley¹, Lynette Moore³, Rebecca Manudhane⁴, Manika Pal⁴, Rebecca Scroop¹, Timothy Kleinig⁵

Affiliations

¹ Royal Adelaide Hospital, Adelaide, Australia.
² Royal Adelaide Hospital, Adelaide, Australia. Electronic address: stephen.bacchi@sa.gov.au.
³ Women's and Children's Hospital, Adelaide, Australia; University of Adelaide, Adelaide, Australia.
⁴ Women's and Children's Hospital, Adelaide, Australia.
⁵ Royal Adelaide Hospital, Adelaide, Australia; University of Adelaide, Adelaide, Australia.

PMID: 31402261
DOI: 10.1016/j.jocn.2019.07.075

Abstract

Optimal treatment for ischaemic stroke in paediatric acute lymphoblastic leukaemia (ALL) is unclear. We describe an ischaemic stroke in an adolescent with ALL who underwent successful endovascular thrombectomy following leukaemic arterial occlusion. Endovascular thrombectomy should be considered in paediatric ALL patients with acute ischaemic stroke and large vessel occlusion.

Keywords: Acute lymphoblastic leukaemia; Endovascular clot retrieval; Endovascular thrombectomy; Hyperviscosity.

Publication types

Case Reports

MeSH terms

Adolescent
Brain Ischemia / surgery
Endovascular Procedures / methods*
Humans
Infarction, Middle Cerebral Artery / etiology*
Infarction, Middle Cerebral Artery / surgery*
Male
Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications*
Thrombectomy / methods*
Treatment Outcome