Gastric neuroendocrine tumour, atrophic gastritis and autoimmune haemolytic anaemia: a case report and review

Scott Med J. 2019 Nov;64(4):154-158. doi: 10.1177/0036933019867574. Epub 2019 Aug 12.

Abstract

Gastric neuroendocrine tumours are rare. We describe a unique case of a 66-year-old male patient who presented with shortness of breath and malaise, eventually attributed to severe autoimmune haemolysis in the context of atrophic gastritis and multiple type-1 gastric neuroendocrine tumours. The patient had also positive anti-cardiolipin antibodies. A favourable outcome was attained with corticosteroids plus subtotal gastrectomy for the treatment of the underlying neoplastic disease. This case illustrates that the differential diagnosis of any associated causes of autoimmune haemolytic anaemia can be challenging, and may extend to unexpected conditions.

Keywords: Autoimmune haemolytic anaemia; anti-cardiolipin antibodies; atrophic gastritis; gastric neuroendocrine; type-1 gastric carcinoid.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Anemia, Hemolytic, Autoimmune / diagnosis*
  • Dyspnea / etiology
  • Fatigue / etiology
  • Gastritis, Atrophic / diagnosis*
  • Humans
  • Male
  • Neuroendocrine Tumors / diagnosis*
  • Stomach Neoplasms / diagnosis*