Functional and clinical characterization of the alternatively spliced isoform AML1-ETO9a in adult patients with translocation t(8;21)(q22;q22.1) acute myeloid leukemia (AML)

Leukemia. 2020 Feb;34(2):630-634. doi: 10.1038/s41375-019-0551-4. Epub 2019 Aug 28.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Alternative Splicing / genetics*
  • Chromosomes, Human, Pair 21 / genetics*
  • Chromosomes, Human, Pair 8 / genetics*
  • Core Binding Factor Alpha 2 Subunit / genetics*
  • Female
  • Humans
  • Leukemia, Myeloid, Acute / genetics*
  • Male
  • Middle Aged
  • Oncogene Proteins, Fusion / genetics*
  • Protein Isoforms / genetics*
  • RUNX1 Translocation Partner 1 Protein / genetics*
  • Translocation, Genetic / genetics*
  • Young Adult

Substances

  • AML1-ETO fusion protein, human
  • Core Binding Factor Alpha 2 Subunit
  • Oncogene Proteins, Fusion
  • Protein Isoforms
  • RUNX1 Translocation Partner 1 Protein