Neonatal tetanus in eastern Uganda: improved outcome following the implementation of a neonatal tetanus protocol

Trop Doct. 2020 Jan;50(1):57-62. doi: 10.1177/0049475519872860. Epub 2019 Aug 31.

Abstract

Neonatal tetanus remains a significant, yet avoidable, cause of neonatal death. Despite the 34,000 deaths that occur globally from neonatal tetanus every year, there has been little research into the management of neonatal tetanus. Until worldwide elimination of neonatal tetanus is achieved, the case management of this devastating illness needs to be improved. We describe an improved outcome of neonatal tetanus following the introduction of a neonatal tetanus protocol including diazepam, magnesium sulphate, bubble continuous positive airway pressure and broad-spectrum antibiotics in a low-resource setting in eastern Uganda.

Keywords: Neonatal tetanus; developing countries; newborn.

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Anticonvulsants / therapeutic use
  • Combined Modality Therapy
  • Continuous Positive Airway Pressure
  • Developing Countries
  • Humans
  • Infant, Newborn
  • Tetanus / epidemiology
  • Tetanus / therapy*
  • Treatment Outcome
  • Uganda / epidemiology

Substances

  • Anti-Bacterial Agents
  • Anticonvulsants