Doctor and patient awareness of treatment options for cervical intraepithelial neoplasia 1 (CIN 1): a survey questionnaire approach

J Obstet Gynaecol. 2020 Feb;40(2):211-216. doi: 10.1080/01443615.2019.1606180. Epub 2019 Sep 1.

Abstract

The purpose of this study was to investigate doctors' and patients' perceptions of cervical intraepithelial neoplasia 1 (CIN 1) and its treatment methods. A survey questionnaire was offered to obstetrics and gynaecology doctors and patients with CIN 1 in 2017. Only 43% of patients knew of this disease. Regarding perceptions of its aetiology, 64% of the patients perceived human papillomavirus infection to be the main cause of CIN 1. Patients' most preferred treatments were medication (20%), followed by alternative treatment (14%). Among doctors, regular follow-up was the most preferred method for managing CIN 1. The survey showed that current treatment modalities for CIN 1 were satisfactory to only half of doctors (50%) and patients (53%). Overall, 70% of doctors responded that new drug development for CIN 1 is needed. Although, CIN 1 is a low-grade lesion, doctors and patients expressed the desire for new therapeutic agents to manage it.IMPACT STATEMENTWhat is already known on this subject? In general, treatment is not recommended for CIN 1 because lesions are considered indicative of transient HPV infection and spontaneously regress in most patients.What do the results of this study add? Regular follow-up for CIN 1 were satisfactory to only half of doctors and patients. Thirty-six percent of patients wanted active treatment instead of regular follow-up. In addition, 70% of doctors responded that new drug development for CIN 1 is needed.What are the implications of these findings for clinical practice and/or further research? Our results support the need for therapeutic agents for CIN 1.

Keywords: Cervical intraepithelial neoplasia 1; doctors; patients; questionnaire; survey; treatment.

MeSH terms

  • Adult
  • Antineoplastic Protocols*
  • Female
  • Gynecology / statistics & numerical data*
  • Health Care Surveys
  • Health Knowledge, Attitudes, Practice
  • Humans
  • Male
  • Middle Aged
  • Obstetrics / statistics & numerical data*
  • Patient Satisfaction / statistics & numerical data*
  • Pregnancy
  • Surveys and Questionnaires
  • Uterine Cervical Dysplasia / psychology*
  • Uterine Cervical Dysplasia / therapy
  • Uterine Cervical Neoplasms / psychology*
  • Uterine Cervical Neoplasms / therapy