Novel quinolone resistance determinant, qepA8, in Shigella flexneri isolated in the United States, 2016

Hattie E Webb; Kaitlin A Tagg; Jessica C Chen; Justin Kim; Rebecca Lindsey; Louise K Francois Watkins; Beth E Karp; Yo Sugawara; Jason P Folster

doi:10.1128/AAC.01458-19

Novel quinolone resistance determinant, qepA8, in Shigella flexneri isolated in the United States, 2016

Antimicrob Agents Chemother. 2019 Sep 9;63(12):e01458-19. doi: 10.1128/AAC.01458-19. Epub 2019 Sep 16.

Authors

Hattie E Webb¹, Kaitlin A Tagg², Jessica C Chen³, Justin Kim⁴, Rebecca Lindsey³, Louise K Francois Watkins³, Beth E Karp³, Yo Sugawara⁵, Jason P Folster³

Affiliations

¹ WDS, Inc; Atlanta, Georgia, USA hwebb@cdc.gov.
² WDS, Inc; Atlanta, Georgia, USA.
³ Division of Foodborne, Waterborne, and Environmental Diseases, Centers for Disease Control and Prevention; Atlanta, Georgia, USA.
⁴ Oak Ridge Institute for Science and Education; Oak Ridge, Tennessee, USA.
⁵ Japan-Thailand Research Collaboration Center on Emerging and Re-emerging Infections, Research Institute for Microbial Diseases, Osaka University; Suita, Japan.

Abstract

Enterobacteriaceae, quinolone resistance is largely attributed to mutations in the quinolone resistance-determining regions (QRDR) of gyrA, gyrB, parC, and parE, and plasmid-italiciated quinolone resistance (PMQR) genes (e.g., qnr genes, aac(6')-Ib-cr, or qepA).….

This is a work of the U.S. Government and is not subject to copyright protection in the United States. Foreign copyrights may apply.

Publication types

Letter