1 Thoracic Oncology, University of Hawaii Cancer Center, 701 Ilalo St, Honolulu, Hawaii, 96813, USA. mcarbone@cc.hawaii.edu.
2 Department of Experimental Medicine, TOR, University of Rome Tor Vergata, 00133, Rome, Italy. gm614@mrc-tox.cam.ac.uk.
3 Medical Research Council, Toxicology Unit, Department of Pathology, Cambridge University, Tennis Court Road, Cambridge, CB2 1QP, UK. gm614@mrc-tox.cam.ac.uk.