Public-private partnerships in transplant drug development

Am J Transplant. 2020 Feb;20(2):377-381. doi: 10.1111/ajt.15604. Epub 2019 Oct 30.

Abstract

The Transplant Therapeutics Consortium (TTC), a public-private partnership (PPP) led by the Critical Path Institute (C-Path), recently published a whitepaper titled "The Importance of Drug Safety and Tolerability in the Development of New Immunosuppressive Therapy for Transplant Recipients" by Stegall et al in the American Journal of Transplantation. As staff members of the Food and Drug Administration's (FDA), Center for Drug Evaluation and Research (CDER), Office of New Drugs and Office of Translational Science, and the Oncology Center of Excellence, we would like to provide our perspective on the TTCs efforts and the whitepaper.

Keywords: clinical trial; editorial/personal viewpoint; kidney transplantation / nephrology; kidney transplantation: living donor.

MeSH terms

  • Drug Development / organization & administration*
  • Graft Rejection / prevention & control*
  • Humans
  • Immunosuppressive Agents / therapeutic use*
  • Organ Transplantation*
  • Public-Private Sector Partnerships / organization & administration*
  • United States
  • United States Food and Drug Administration / organization & administration

Substances

  • Immunosuppressive Agents