[Precision medicine in hematological malignancies]

Rinsho Ketsueki. 2019;60(9):1386-1395. doi: 10.11406/rinketsu.60.1386.
[Article in Japanese]

Abstract

Precision medicine is a type of medical care designed to optimize the therapeutic efficiency or benefit for particular groups of patients with the use of genetic profiling. The application of precision medicine in cancer treatment is prospected because cancer is reported to be the leading cause of death in Japan. Consequently, Japanese cancer genome medicine will be launched within this fiscal year. In this study, we focus on precision medicine specifically in the field of hematological malignancies with an overview of its clinical utility. We further discuss how precision medicine should be developed in this field, based on our experience of a feasibility study for clinical sequencing in hematological malignancies.

Keywords: Clinical sequence; Expert panel; Hematological malignancies; Potentially actionable finding.

Publication types

  • Review

MeSH terms

  • Hematologic Neoplasms*
  • Humans
  • Japan
  • Precision Medicine*