Disseminated Cutaneous and Osteoarticular Sporotrichosis Mimicking Pyoderma Gangrenosum

Lina Saeed; Robert J Weber; Sarah B Puryear; Eman Bahrani; Michael J Peluso; Jennifer M Babik; Anna Haemel; Sarah J Coates

doi:10.1093/ofid/ofz395

Disseminated Cutaneous and Osteoarticular Sporotrichosis Mimicking Pyoderma Gangrenosum

Open Forum Infect Dis. 2019 Sep 9;6(10):ofz395. doi: 10.1093/ofid/ofz395. eCollection 2019 Oct.

Authors

Lina Saeed^{1

2}, Robert J Weber¹, Sarah B Puryear^{1

3}, Eman Bahrani^{1

2}, Michael J Peluso^{1

3}, Jennifer M Babik^{1

3}, Anna Haemel^{1

2}, Sarah J Coates^{1

2}

Affiliations

¹ School of Medicine, University of California San Francisco, San Francisco, California, USA.
² Department of Dermatology, University of California San Francisco, San Francisco, California, USA.
³ Division of Infectious Disease, University of California San Francisco, San Francisco, California, USA.

Abstract

Disseminated sporotrichosis may present with inflammatory arthritis and cutaneous ulcerations that mimic noninfectious skin conditions such as pyoderma gangreonsum (PG). Sporotrichosis must therefore be ruled out before administering immunosuppressive agents for PG. Furthermore, dimorphic fungi such as sporotrichosis may grow as yeast in bacterial cultures, even before fungal cultures become positive. We present a case of disseminated cutaneous and osteoarticular sporotrichosis mimicking PG and describe the differential diagnosis and the diagnostic and treatment approach to this condition.

Keywords: Sporothrix; United States of America; deep fungal infection; disseminated fungal infection; septic arthritis; ulcer.

Publication types

Case Reports

Grants and funding

T32 MH019105/MH/NIMH NIH HHS/United States