New tick-borne encephalitis virus hot spot in Northern Zealand, Denmark, October 2019

Euro Surveill. 2019 Oct;24(43):1900639. doi: 10.2807/1560-7917.ES.2019.24.43.1900639.

Abstract

During summer 2019, three patients residing by Tisvilde Hegn, Denmark were hospitalised with tick-borne encephalitis (TBE) after tick bites. A new TBE virus (TBEV) micro-focus was identified in tick nymphs collected around a playground in Tisvilde Hegn forest. Estimated TBEV prevalence was 8%, higher than in endemic areas around Europe. Whole genome sequencing showed clustering to a TBEV strain from Norway. This is the second time TBEV is found in Ixodes ricinus outside Bornholm, Denmark.

Keywords: Denmark; Ixodes ricinus; Northern Zealand; Tick-borne encephalitis; meningoencephalitis; phylogenetic analysis; tick-borne encephalitis virus.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Animals
  • Encephalitis Viruses, Tick-Borne / genetics
  • Encephalitis Viruses, Tick-Borne / isolation & purification*
  • Encephalitis, Tick-Borne / diagnosis*
  • Female
  • Fever / etiology
  • Headache / etiology
  • Humans
  • Immunoglobulin G / blood
  • Immunoglobulin M / blood
  • Ixodes / virology*
  • Male
  • Middle Aged
  • RNA, Viral / genetics*
  • RNA, Viral / isolation & purification
  • Whole Genome Sequencing

Substances

  • Immunoglobulin G
  • Immunoglobulin M
  • RNA, Viral