Adolescent rat social play: Amygdalar proteomic and transcriptomic data

Navatha Alugubelly; Afzaal N Mohammed; Mariola J Edelmann; Bindu Nanduri; Mohammed Sayed; Juw Won Park; Russell L Carr

doi:10.1016/j.dib.2019.104589

Adolescent rat social play: Amygdalar proteomic and transcriptomic data

Data Brief. 2019 Sep 30:27:104589. doi: 10.1016/j.dib.2019.104589. eCollection 2019 Dec.

Authors

Navatha Alugubelly^{1

2}, Afzaal N Mohammed^{1

2}, Mariola J Edelmann³, Bindu Nanduri², Mohammed Sayed⁴, Juw Won Park^{4

5}, Russell L Carr^{1

2}

Affiliations

¹ Center for Environmental Health Sciences, USA.
² Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, MS, USA.
³ Department of Microbiology and Cell Science, University of Florida, Gainesville, FL, USA.
⁴ Department of Computer Engineering and Computer Science, USA.
⁵ KBRIN Bioinformatics Core, University of Louisville, KY, USA.

Abstract

This data article contains the proteomic and transcriptomic data of the amygdala of adolescent rats involved in social play compared to non-behavioural animals. Social play was performed on male Sprague Dawley rats on postnatal day 38 and protein and gene expression in the amygdala was determined following behavioural testing. The protein expression was measured by analysing trypsin digested protein samples using a LTQ Orbitrap Velos mass spectrometer equipped with an Advion nanomate ESI source. The obtained tandem mass spectra were extracted by Thermo Proteome Discoverer 1.3 and the data were displayed with Scaffold v 4.5.1. The transcriptomic data were generated by llumina HiSeq 4000 system. Cuffdiff (v2.2.1) program was used to calculate RNA-seq based gene expression levels. For further interpretation of data presented in this article, please see the research article 'Proteomic and Transcriptional Profiling of Rat Amygdala Following Social Play' (Alugubelly et al. 2019).

Keywords: Amygdala; Behaviour; Proteome; Social play; Transcriptome.

Abstract

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