Protection against noise trauma by pre-exposure to a low level acoustic stimulus

B Canlon; E Borg; A Flock

doi:10.1016/0378-5955(88)90107-4

Protection against noise trauma by pre-exposure to a low level acoustic stimulus

Hear Res. 1988 Jul 15;34(2):197-200. doi: 10.1016/0378-5955(88)90107-4.

Authors

B Canlon¹, E Borg, A Flock

Affiliation

¹ Department of Physiology II, Karolinska Institute, Stockholm, Sweden.

PMID: 3170362
DOI: 10.1016/0378-5955(88)90107-4

Abstract

Guinea pigs were pre-exposed to a low level acoustic stimulus prior to exposure to a stimulus known to yield a permanent threshold shift. This pre-treatment resulted in: 1) approximately a 20 dB reduction in the threshold shift relative to animals not pre-exposed, and 2) complete recovery from the threshold shift after 2 months.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acoustic Stimulation*
Animals
Auditory Fatigue / physiology
Auditory Threshold / physiology
Evoked Potentials, Auditory
Guinea Pigs
Hearing Loss, Noise-Induced / physiopathology*
Hearing Loss, Noise-Induced / prevention & control