Feasibility trial of a digital self-management intervention 'My Breathing Matters' to improve asthma-related quality of life for UK primary care patients with asthma

BMJ Open. 2019 Nov 12;9(11):e032465. doi: 10.1136/bmjopen-2019-032465.

Abstract

Objective: To assess the feasibility of a randomised controlled trial (RCT) and acceptability of an asthma self-management digital intervention to improve asthma-specific quality of life in comparison with usual care.

Design and setting: A two-arm feasibility RCT conducted across seven general practices in Wessex, UK.

Participants: Primary care patients with asthma aged 18 years and over, with impaired asthma-specific quality of life and access to the internet.

Interventions: 'My Breathing Matters' (MBM) is a digital asthma self-management intervention designed using theory, evidence and person-based approaches to provide tailored support for both pharmacological and non-pharmacological management of asthma symptoms.

Outcomes: The primary outcome was the feasibility of the trial design, including recruitment, adherence and retention at follow-up (3 and 12 months). Secondary outcomes were the feasibility and effect sizes of specific trial measures including asthma-specific quality of life and asthma control.

Results: Primary outcomes: 88 patients were recruited (target 80). At 3-month follow-up, two patients withdrew and six did not complete outcome measures. At 12 months, two withdrew and four did not complete outcome measures. 36/44 patients in the intervention group engaged with MBM (median of 4 logins, range 0-25, IQR 8). Consistent trends were observed to improvements in asthma-related patient-reported outcome measures.

Conclusions: This study demonstrated the feasibility and acceptability of a definitive RCT that is required to determine the clinical and cost-effectiveness of a digital asthma self-management intervention.

Trial registration number: ISRCTN15698435.

Keywords: asthma; breathing retraining; digital; primary care; quality of life; self-management.

Publication types

  • Pragmatic Clinical Trial
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Asthmatic Agents / therapeutic use
  • Asthma / drug therapy
  • Asthma / psychology*
  • Asthma / rehabilitation*
  • Cost-Benefit Analysis
  • Feasibility Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Patient Compliance
  • Patient Education as Topic
  • Patient Satisfaction
  • Primary Health Care / economics
  • Primary Health Care / methods*
  • Quality of Life*
  • Self-Management*
  • Social Support*
  • Software*
  • United Kingdom

Substances

  • Anti-Asthmatic Agents

Associated data

  • ISRCTN/ISRCTN15698435