Linear IgA dermatosis of the childhood-Report of an amoxicillin-induced case

Dermatol Ther. 2020 Jan;33(1):e13173. doi: 10.1111/dth.13173. Epub 2019 Dec 4.

Abstract

Linear IgA dermatosis (LAD) is a rare autoimmune disorder in children. A 9-year-old boy was presented with blisters on the intact skin (face, body, arms, hands, soles, perigenital and perianal area) after amoxicillin treatment. Systemic corticosteroids and dapsone treatment for 6 weeks was successful. Clinical and immunofluorescence examinations are most important for differentiation of LAD and other drug-induced bullous dermatoses. They enable an early introduction of proper therapy.

Keywords: child; chronic bullous disease; linear IgA bullous dermatosis; skin diseases.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amoxicillin / administration & dosage
  • Amoxicillin / adverse effects*
  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / adverse effects*
  • Child
  • Dapsone / administration & dosage
  • Glucocorticoids / administration & dosage
  • Humans
  • Linear IgA Bullous Dermatosis / chemically induced*
  • Linear IgA Bullous Dermatosis / diagnosis
  • Linear IgA Bullous Dermatosis / pathology
  • Male
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Glucocorticoids
  • Amoxicillin
  • Dapsone