Local Control of Perineal Rhabdomyosarcoma: Are Current Recommendations Adequate?

Urology. 2020 Mar:137:161-163. doi: 10.1016/j.urology.2019.11.011. Epub 2019 Nov 23.

Abstract

Rhabdomyosarcoma (RMS) is a rare malignancy that can develop in nearly any soft-tissue of the body. Location of the primary tumor affects treatment strategy and prognosis, and RMS of the perineal areas can be especially difficult to treat successfully. RMS is treated systemically with chemotherapy. Local control options include surgical excision, radiation treatment, or a combination of the 2. Treating RMS with radiation treatment can be challenging due to the absence of standardized dosage protocols, along with the presence of conflicting recommendations in the literature. Each case of perineal RMS may benefit from a more individualized treatment plan.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage*
  • Bone Marrow Examination / methods
  • Groin
  • Humans
  • Lymph Nodes / pathology*
  • Lymphatic Metastasis* / drug therapy
  • Lymphatic Metastasis* / radiotherapy
  • Magnetic Resonance Imaging / methods
  • Male
  • Neoplasms, Gonadal Tissue* / drug therapy
  • Neoplasms, Gonadal Tissue* / pathology
  • Neoplasms, Gonadal Tissue* / radiotherapy
  • Perineum / pathology*
  • Positron Emission Tomography Computed Tomography / methods
  • Proton Therapy / methods*
  • Rhabdomyosarcoma, Alveolar* / drug therapy
  • Rhabdomyosarcoma, Alveolar* / pathology
  • Rhabdomyosarcoma, Alveolar* / radiotherapy
  • Treatment Outcome