Abstract
High CD8 T-cells and low CD4/CD8 are associated with lower lung function among youth living with perinatally-acquired HIV, despite antiretroviral therapy and CD4 preservation/reconstitution. Understanding these underlying mechanisms is critical to mitigate lung function impairment.
Publication types
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Letter
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Multicenter Study
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adult
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CD4-Positive T-Lymphocytes / immunology
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CD8-Positive T-Lymphocytes / immunology
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Child
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Female
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Forced Expiratory Volume
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HIV Infections* / immunology
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HIV Infections* / physiopathology
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HIV Infections* / transmission
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Humans
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Infectious Disease Transmission, Vertical*
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Kenya
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Lung / physiopathology
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Lymphocyte Count
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Male
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United States
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Young Adult