Epigenome-Wide Association Study Identifies a Novel DNA Methylation in Patients With Severe Aortic Valve Stenosis

Circ Genom Precis Med. 2020 Feb;13(1):e002649. doi: 10.1161/CIRCGEN.119.002649. Epub 2020 Jan 12.
No abstract available

Keywords: cardiovascular diseases; demethylation; informed consent; leukocyte count; tricuspid valve.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aortic Valve Stenosis / genetics*
  • Aortic Valve Stenosis / pathology*
  • Case-Control Studies
  • DNA Methylation*
  • Epigenome*
  • Gene Expression Regulation*
  • Humans
  • Intracellular Signaling Peptides and Proteins / genetics*
  • Protein Serine-Threonine Kinases / antagonists & inhibitors*
  • Protein Serine-Threonine Kinases / genetics
  • Severity of Illness Index*

Substances

  • Intracellular Signaling Peptides and Proteins
  • TRIB1 protein, human
  • Protein Serine-Threonine Kinases