Craniovertebral junction fixation in children less than 5 years

Eur Spine J. 2020 May;29(5):961-969. doi: 10.1007/s00586-020-06313-x. Epub 2020 Feb 3.

Abstract

Purpose: Whilst rigid fixation for craniovertebral instability is the gold standard, in very young, small children conventional management may have to be modified. We present a single-centre experience of craniocervical fixation in children under 5 years.

Methods: A retrospective review of cases that had undergone atlantoaxial (AA) or occipitocervical (OC) fixation aged under 5 years. Fusion was assessed using computerised tomography or flexion extension X-rays.

Results: Twenty-six children (median age 2.3, range 0.8-4.9 years, 19 under the age of 3) underwent OC (n = 19) or AA (n = 7) fusion between 1999 and 2016. Pathology comprised 17 congenital, five trauma, two tumour and two post-infection cases. Twenty-one patients underwent sublaminar cable fixation with calvarial, autologous bone graft and halo-body orthosis immobilisation. An occipital plate and rods to sublaminar wire construct were used in four cases. A rigid instrumented fixation with occipital plate and C2 pedicle screws was utilised in one case. Follow-up was for a median of 2.8 years (range 0.03-16.3 years). Initial fusion rate was 91%, reaching 100% following two re-operations. Ninety-two per cent of patients were neurologically stable or improved following surgery. Twenty-one patients had a good overall outcome. Two patients had post-operative neurological deteriorations, and four died due to non-procedure related causes. Pin site morbidity secondary to halo use occurred in five cases.

Conclusion: High fusion rates with good outcomes are achievable using semi-rigid fixation in the under 5-year-olds. Full thickness, autologous calvarial bone graft secured with wire cables and halo external orthosis offers a safe and effective alternative technique when traditional screw instrumentation is not feasible. These slides can be retrieved under Electronic Supplementary Material.

Keywords: Craniovertebral; Paediatrics; Semi-rigid fixation; Spine.

MeSH terms

  • Atlanto-Axial Joint* / diagnostic imaging
  • Atlanto-Axial Joint* / surgery
  • Bone Plates
  • Cervical Vertebrae / diagnostic imaging
  • Cervical Vertebrae / surgery
  • Child, Preschool
  • Humans
  • Infant
  • Joint Instability* / surgery
  • Radiography
  • Reoperation
  • Retrospective Studies
  • Spinal Fusion*
  • Treatment Outcome