β-Cyclodextrin-Immobilized Ni/Graphene Electrode for Electrochemical Enantiorecognition of Phenylalanine

Feiyue Chen; Zhiqin Fan; Yangguang Zhu; Huifang Sun; Jinhong Yu; Nan Jiang; Shichao Zhao; Guosong Lai; Aimin Yu; Cheng-Te Lin; Chen Ye; Li Fu

doi:10.3390/ma13030777

β-Cyclodextrin-Immobilized Ni/Graphene Electrode for Electrochemical Enantiorecognition of Phenylalanine

Materials (Basel). 2020 Feb 8;13(3):777. doi: 10.3390/ma13030777.

Authors

Feiyue Chen^{1

2}, Zhiqin Fan¹, Yangguang Zhu^{2

3}, Huifang Sun^{2

4}, Jinhong Yu^{2

5}, Nan Jiang^{2

5}, Shichao Zhao⁶, Guosong Lai⁷, Aimin Yu^{7

8}, Cheng-Te Lin^{2

5}, Chen Ye^{2

5}, Li Fu⁶

Affiliations

¹ College of Science, Henan University of Technology, Zhengzhou 450001, China.
² Key Laboratory of Marine Materials and Related Technologies, Zhejiang Key Laboratory of Marine Materials and Protective Technologies, Ningbo Institute of Materials Technology and Engineering (NIMTE), Chinese Academy of Sciences, Ningbo 315201, China.
³ Laboratory of Environmental Biotechnology, School of Environmental and Civil Engineering, Jiangnan University, Wuxi 214122, China.
⁴ Faculty of Materials Science and Engineering, Kunming University of Science and Technology, Kunming 650093, China.
⁵ Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences, Beijing 100049, China.
⁶ College of Materials and Environmental Engineering, Hangzhou Dianzi University, Hangzhou 310018, China.
⁷ Department of Chemistry, Hubei Normal University, Huangshi 435002, China.
⁸ Department of Chemistry and Biotechnology, Faculty of Science, Engineering and Technology, Swinburne University of Technology, Hawthorn VIC 3122, Australia.

Abstract

In this work, a Ni/graphene (Ni/G) electrode was designed and fabricated by plasma-enhanced chemical vapor deposition (PECVD) for the ultrasensitive recognition of d- and l-phenylalanine. Through a single-step PECVD process, the Ni/G electrode can achieve better hydrophilicity and larger catalytic surface area, which is beneficial for the electrochemical recognition of bio-objects. After surface modification with β-cyclodextrin, the Ni/G electrode can distinguish d-phenylalanine from l-phenylalanine according to a 0.09 V peak shift in differential pulse voltammetry tests. Moreover, this Ni/G electrode achieved a detection limit as low as 1 nM and a wide linear range from 1 nM to 10 mM toward l-phenylalanine, with great storage stability and working stability.

Keywords: enantiorecognition; graphene; phenylalanine; plasma-enhanced chemical vapor deposition; β-cyclodextrin.

Abstract

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