Acute myeloid leukaemia with maturation demonstrates persistent disease with prominent megakaryoblastic differentiation 16 days following induction chemotherapy: an intra-myeloid lineage switch mediated by chemotherapy-induced clonal selection

Br J Haematol. 2020 May;189(3):e64-e67. doi: 10.1111/bjh.16476. Epub 2020 Feb 28.

Yue Zhao^{1

2}, Jake Maule², Jenna McCracken², Yang Li^{2

3}, Sarah Rapisardo², Lian-He Yang^{1

2}, Endi Wang²

¹ Department of Pathology, College of Basic Medical Sciences and First Affiliated Hospital of China Medical University, Shenyang, People's Republic of China.
² Department of Pathology, Duke University School of Medicine, Durham, NC, USA.
³ Division of Haematology/Oncology, Department of Medicine, Shengjing Hospital Affiliated to China Medical University, Shenyang, People's Republic of China.

No abstract available

Keywords: acute megakaryoblastic leukaemia; acute myeloid leukaemia; clonal selection; intra-myeloid lineage switch; lineage switch.

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