Transarterial radioembolization for liver tumors as neoadjuvant therapy: three case reports

Einstein (Sao Paulo). 2020 Feb 27:18:eRC4990. doi: 10.31744/einstein_journal/2020RC4990. eCollection 2020.
[Article in English, Portuguese]

Abstract

Transarterial radioembolization (TARE) with yttrium-90 microspheres is a palliative locoregional treatment, minimally invasive for liver tumors. The neoadjuvant aim of this treatment is still controversial, however, selected cases with lesions initially considered unresectable have been enframed as candidates for curative therapy after hepatic transarterial radioembolization. We report three cases in which the hepatic transarterial radioembolization was used as neoadjuvant therapy in an effective way, allowing posterior potentially curative therapies.

RESUMO: A radioembolização transarterial hepática com microesferas de ítrio-90 é uma modalidade paliativa de tratamento locorregional minimamente invasiva. O objetivo neoadjuvante deste tratamento ainda é controverso, mas casos selecionados de lesões consideradas inicialmente irressecáveis reenquadram-se como candidatos à terapia curativa após a radioembolização transarterial hepática. Relatamos três casos em que a radioembolização transarterial hepática foi utilizada como terapia neoadjuvante de forma efetiva possibilitando aplicação posterior de terapias potencialmente curativas.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Bile Duct Neoplasms / therapy*
  • Carcinoma, Hepatocellular / therapy*
  • Chemoembolization, Therapeutic / methods*
  • Cholangiocarcinoma / therapy*
  • Disease Progression
  • Female
  • Humans
  • Liver Neoplasms / therapy*
  • Male
  • Middle Aged
  • Neoadjuvant Therapy / methods
  • Treatment Outcome
  • Yttrium Radioisotopes

Substances

  • Yttrium Radioisotopes
  • Yttrium-90