Dataset of allele, genotype and haplotype frequencies of four polymorphisms filaggrin gene in Russian patients with atopic dermatitis

Tatyana Belyaeva; Irina Ponomarenko; Evgeny Reshetnikov; Alexey Polonikov; Inna Aristova; Anna Elykova; Natalya Rudykh; Mikhail Churnosov

doi:10.1016/j.dib.2020.105307

Dataset of allele, genotype and haplotype frequencies of four polymorphisms filaggrin gene in Russian patients with atopic dermatitis

Data Brief. 2020 Feb 21:29:105307. doi: 10.1016/j.dib.2020.105307. eCollection 2020 Apr.

Authors

Tatyana Belyaeva¹, Irina Ponomarenko¹, Evgeny Reshetnikov¹, Alexey Polonikov², Inna Aristova¹, Anna Elykova¹, Natalya Rudykh¹, Mikhail Churnosov¹

Affiliations

¹ Department of Medical Biological Disciplines, Belgorod State University, 308015, Belgorod, Russia.
² Department of Biology, Medical Genetics and Ecology, Kursk State Medical University, 305041, Kursk, Russia.

Abstract

Data on the allele, genotype and haplotype frequencies of four single nucleotide polymorphisms (SNPs) (rs3126085, rs12144049, rs471144 and rs4363385) filaggrin (FLG) gene in Russian patients with atopic dermatitis are presented. Genome-wide association studies identified these SNPs could be significant genetic markers associated with atopic dermatitis. The frequencies of alleles, genotypes and haplotypes of four SNPs were calculated in 3 groups: entire sample, females and males. No significant differences in the allele, genotype and haplotype frequencies between males and females with AD patients were observed.

Keywords: Atopic dermatitis; FLG; Female; Male; Single nucleotide polymorphism.