Exercise ameliorates post-stroke depression by inhibiting PTEN elevation-mediated upregulation of TLR4/NF-κB/NLRP3 signaling in mice

Brain Res. 2020 Jun 1:1736:146777. doi: 10.1016/j.brainres.2020.146777. Epub 2020 Mar 22.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Depression / metabolism
  • Depression / physiopathology
  • Depression / therapy*
  • Male
  • Mice
  • Mice, Inbred C57BL
  • NF-kappa B / metabolism
  • NLR Family, Pyrin Domain-Containing 3 Protein / metabolism
  • PTEN Phosphohydrolase / metabolism*
  • Physical Conditioning, Animal / methods
  • Physical Conditioning, Animal / psychology*
  • Signal Transduction / physiology
  • Stroke / physiopathology
  • Stroke / psychology
  • Toll-Like Receptor 4 / metabolism

Substances

  • NF-kappa B
  • NLR Family, Pyrin Domain-Containing 3 Protein
  • Nlrp3 protein, mouse
  • Tlr4 protein, mouse
  • Toll-Like Receptor 4
  • PTEN Phosphohydrolase
  • Pten protein, mouse