[Management of hemodialysis patient subject to medical-nuclear investigation]

G Ital Nefrol. 2020 Apr 9;37(2):2020-vol2.
[Article in Italian]

Abstract

In recent years imaging techniques that use radionuclides have become more and more clinically relevant as they can provide functional information for specific anatomical districts. This has also involved nephrology, where radionuclides are used to study patients with different degrees of renal function failure up to terminal uremia. Although chronic kidney disease, and dialysis in particular, may affect the distribution and the elimination of radiopharmaceuticals, to date there are no consistent data on the risks associated with their use in this clinical context. In addition to the lack of data on the safety of radio-exposure in dialysis patients, there is also a shortage of information concerning the risk for healthcare staff involved in conducting the dialysis sessions performed after a nuclear test. This study, performed on 29 uremic patients who underwent hemodialysis immediately after a scintigraphic examination, assessed the extent of radio-contamination of the staff and of hemodialysis devices such as monitor, kits and dialysate. The data collected has been used to quantify the radiological risk in dialysis after the exposure to the most common radionuclides.

Keywords: chronic kidney disease; hemodialysis; imaging; radiological risk; radionuclides; scintigraphy.

MeSH terms

  • Dialysis Solutions / chemistry
  • Dialysis Solutions / metabolism
  • Humans
  • Kidney Failure, Chronic / diagnostic imaging*
  • Kidney Failure, Chronic / metabolism
  • Radionuclide Imaging / adverse effects
  • Radionuclide Imaging / methods
  • Radiopharmaceuticals / adverse effects
  • Radiopharmaceuticals / metabolism*
  • Renal Dialysis*
  • Risk Assessment
  • Uremia / metabolism

Substances

  • Dialysis Solutions
  • Radiopharmaceuticals