Knockout of the Murine Ortholog to the Human 9p21 Coronary Artery Disease Locus Leads to Smooth Muscle Cell Proliferation, Vascular Calcification, and Advanced Atherosclerosis

Circulation. 2020 Apr 14;141(15):1274-1276. doi: 10.1161/CIRCULATIONAHA.119.043413. Epub 2020 Apr 13.

Authors

Affiliations

¹ Department of Surgery, Division of Vascular Surgery (Y.K., J.Y., V.N., Y.W., A.M.F., K.-U.J., P.T., N.J.L.), Stanford University School of Medicine, CA.
² CVPath Institute, Gaithersburg, MD (L.G., A.V.F., R.V.).
³ Department of Medicine, Division of Cardiovascular Medicine (N.J.L.), Stanford University School of Medicine, CA.

No abstract available

Keywords: atherosclerosis; chromosomes; coronary artery disease; genetics; vascular calcification.

Publication types

Letter
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Atherosclerosis / physiopathology*
Cell Proliferation
Coronary Artery Disease / physiopathology*
Female
Humans
Male
Mice
Myocytes, Smooth Muscle / pathology*
Vascular Calcification / physiopathology*

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